Anti-CD81 [1.3.3.22]

Catalogue Number: AB01547-13.12-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:TSPAN-28; Tetraspanin-28; TSPAN28; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; TAPA-1; TAPA1
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Human
Clone: 1.3.3.22
Isotype: IgG4
Immunogen: This antibody was raised by immunizing mice with a B-Cell line derived from a Burkitt lymphoma.
Application: FACS, FC, IF, WB, IHC

Additional Text

Gene Name

CD81

Gene ID

975

Uniprot ID

P60033

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas and thus 1.3.3.22 can be used as a research antibody in the studies on lymphoma therapeutics. This antibody is also recommended in the detection and analysis of CD81 via various methods. For instance, 1.3.3.22 antibody was used in the identification of CD81 in human arteries by immunohistochemistry (Rohlena et al., 2009). 1.3.3.22 was also successfully utilized during flow cytometric detection of CD81 on KM3 cells (Higginbottom et al., 2000).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.