Anti-B7-H6 [17B1.3]

Catalogue Number: AB01574-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:B7H6; B7 homolog 6; Natural cytotoxicity triggering receptor 3 ligand 1; NCR3LG1; DKFZp686O2416
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: 17B1.3
Isotype: IgG
Immunogen: Immunised mice with extracellular domain of human B7-H6 and selected on the basis of specific reactivity by P815.B7-H6, but not with P815.B7-H1.
Application: FC, IF, Crstion

Additional Text

Gene ID

374383

Gene Name

NCR3LG1

Uniprot ID

Q68D85

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

B7-H6 is not detected in normal human tissues at steady state but is expressed on tumour cells, so tumour cells can be detected by NK cells. This article describes the study of the mechanisms that govern the induction of B7-H6 on primary cells as well as its consequences in vitro and in vivo.

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.