Anti-desmoglein-3 [5G11]

Catalogue Number: AB01659-10.3-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:PVA; Cadherin family member 6; desmoglein 3; 130 kDa pemphigus vulgaris antigen; DSG3
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: 5G11
Isotype: IgG1
Immunogen: This antibody was raised by immunizing Balb/c mice with a recombinant protein corresponding to human desmoglein-3.
Application: FC, IF, IP, WB, DB, IHC

Additional Text

Gene Name

DSG3

Gene ID

1830

Uniprot ID

P32926

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody can be used for detection and analysis of desmoglein-3 via various methods. For instance, 5G11 was utilized todetect desmoglein-3 in human scalp hair follicles and epidermal inclusions via immunohistochemistry (Wu et al., 2003). Another group successfully used this antibody to identify desmoglein-3 via Western blot (Mao et al., 2017; pmid: 28469076). The antibody 5G11 was also used to detect DSG3 in cells via immunofluorescence (Chen et al., 2013; pmid: 23737966).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.