Anti-MERS-CoV Spike protein [3B12]

Catalogue Number: AB01673-10.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Spike gylcoprotein; S glycoprotein; E2; Peplomer protein;Spike protein S1
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: 3B12
Isotype: IgG1
Immunogen: The original antibody was generated by isolating neutralizing antibodies from a non-immune human Ab-phage library using a novel panning strategy.
Application: NT

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

UniProt ID

W6A028

Application Notes

This antibody blocks the binding of MERS-CoV spike protein to DPP4 receptor by binding to the aa 349-590 in the S1 domain of the MERS-CoV. It is a neutralizing antibody with IC50 value ranging from 1.25 to 2 µg/mL.