Anti-CD11b [ICRF44]
Catalogue Number: AB01998-10.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; mAb 44; mAb44 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | ICRF44 |
| Isotype: | IgG1 |
| Immunogen: | The original mouse IgG1 version of this antibody was raised against the rheumatoid synovial cells and human monocytes. |
| Application: | FC, IP, WB, IHC |
Additional Text
Gene Name
ITGAM
Gene ID
3684
Uniprot ID
P11215
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody is recommended for the detection and analysis of CD11b (Integrin alpha-M) and CD11b-plus cells in lineage identification. The original mouse IgG1 format of this clone has been widely used in various flow cytometry experiments. For instance, ICRF44 was applied in an FC analysis of cells during MDSCs' generation (Eriksson et al., 2019; pmid: 30617223). Another group screened mouce splenocytes with this antibody during tumor studies (Horn et al., 2017; pmid: 28938530). Jardine et al. (2019) utilized this clone to phenotype blood DC cells (pmid: 31040289). Similarly, this antibody was used as a part of a wider panel to phenotype MUTZ-3 and MUTZ-LCs cells (Bock et al., 2016; pmid: 26794428).
Short Description
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB01998-10.0 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations