Anti-Spike protein (RBD) [Sb#68]

Catalogue Number: AB02017-34.11-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Camelid
Clone:	Sb#68
Isotype:
Immunogen:	This clone was originally isolated in a form of a synthetic nanobody (sybody) via a 'target swap' selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds.
Application:	ELISA, Inh

Overview
Datasheets

Additional Text

Gene Name

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Gene ID

43740568

Uniprot ID

P0DTC2

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Specificity

SARS CoV 2 S glycoprotein; Sb68; COVID-19 Spike protein; RBD; Receptor Binding Domain; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV; SARS-CoV2

Application Notes

This antibody is recommended for detection of SARS CoV 2 or 2019-nCoV. Sb#68 is a strong binder and binds the 2019-nCoV ectodomain with an affinity of KD ~ 37 nM (Walter et al., 2020). The initial characterization and binding activity of this antibody to SARS CoV2 spike protein was confirmed with ELISA (Walter et al., 2020). This antibody is a mild inhibitor for interaction between hACE2 and RBD of SARS CoV2. This clone binds to a non-overlapping epitope relative to S#15 (Ab02013) what can be used in develoepment of anti-Covid-19 therapuetics granting together increased avidity to the spike protein (Walter et al., 2020).

AB02017-34.11 Datasheet

Price

£525.00

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Quantity
Unit Size

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