Anti-CD20 [RF2]

Catalogue Number: AB02037-201.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:B-lymphocyte antigen CD20; Membrane-spanning 4-domains subfamily A member 1; MS4A1
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Dog
Clone: RF2
Isotype: IgG2
Immunogen: The original antibody was generated by immunizing mice with cyclic canine CD20 peptide.
Application: ELISA

Additional Text

Gene Name

MS4A1

Purification

Purified

Gene ID

485430

Uniprot ID

Q3C2E2

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

CD20 is an established marker or target for B-cell lymphomas due to the expression of this antigen at high levels on malignant B cells which are associated with B cell lymphoma. This antibody is recommended for diagnosis and may be used for treatment of lymphomas and other immune mediated diseases in dogs and cats. RF2 is capable of binding canine, feline, murine and human CD20 in an ELISA (US20140294819). This antibody is also available in caninized and felinized versions on request.

Short Description

This chimeric dog antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.