Anti-Pan-Nav channel [K58/35]

Catalogue Number: AB02113-23.0-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	K58/35R; sodium voltage-gated channel; Na+ channel
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Rabbit
Clone:	K58/35
Isotype:	IgG
Immunogen:	This antibody was raised by immunising mice with a synthetic peptide corresponding to a highly conserved segment of the intracellular III-IV loop of vertebrate Na+ channels.
Application:	WB, IHC, IB

Overview
Datasheets

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody has been used to stain teased axons prepared from rat spinal nerves (Devaux, 2012), sections of rat retina (Wart et al, 2005) and mice optic nerve cryosections (Vega et al, 2008) for Nav expression. This antibody has been shown to label Nav channels concentrated on the axon initial segment and nodes of Ranvier (Andrews et al, 2019). This antibody has been used in immunoblot analysis of rat brain membranes (Wart et al, 2005; Vega et al, 2013), and to stain COS-1 cells transfected with Nav1 cDNA (Wart et al, 2005). Additionally, this antibody has been used in western blot analysis of mice optic nerve and brain membrane proteins (Vega et al, 2008).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB02113-23.0 Datasheet

Price

£390.00

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