Anti-Nav1.1 Na+ channel [K74/71]

Catalogue Number: AB02116-1.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:K74/71R; Voltage-gated sodium channel subunit alpha Nav1.1; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Scn1a; NAC1; SCN1
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Mouse
Clone: K74/71
Isotype: IgG1
Immunogen: This antibody was raised by immunising BALB/c mice with a fusion protein consisting of the cytoplasmic C-terminus (amino acids 1929-2009) of rat Nav1.1.
Application: ELISA, IF, IP, IHC, IB

Additional Text

Gene Name

SCN1A

Uniprot ID

P04774

Gene ID

81574

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The specificity of this antibody has been confirmed in ELISA against the GST-Nav1.1 fusion protein and immunofluorescence analysis of COS cells expressing full-length human Nav1.1 (Van Wart et al, 2005). This antibody has been used in immunoblot analysis of adult rat brain membranes, where it labels a single band at the same position as that labelled with pan-specific anti-Nav antibody K58/35 (Van Wart et al, 2005). Additionally, this antibody has been used in immunohistochemical analysis of adult rat hippocampus and whole brain sections (Van Wart et al, 2005; Andrews et al, 2019; PMID:30667360).