Anti-Kv4.3 K+ Channel [K75/41]

Catalogue Number: AB02117-10.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:K75/41R; Potassium voltage-gated channel subfamily D member 3; Kcnd3
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: K75/41
Isotype: IgG1
Immunogen: This antibody was raised by immunising BALB/c mice with a fusion protein consisting of the cytoplasmic C-terminus (amino acids 415-636) of rat Kv4.3.
Application: IHC, IB

Additional Text

Gene Name

KCND3

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Uniprot ID

Q62897

Gene ID

65195

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The specificity of this antibody has been confirmed in immunohistochemical analysis; while this antibody stains adult rat hippocampus sections (Andrews et al, 2019; PMID:30667360), brain sections from Kv4.3-/- mice remain blank (Burkhalter et al, 2006). This antibody has been used in immunoblot analysis of rat, mouse and frog brain membranes (Andrews et al, 2019; PMID:30667360). Additionally, this antibody has been used to assess Kv4.3 expression in mouse primary visual and primary somatosensory cortex through immunofluorescence imaging (Burkhalter et al, 2006).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.