Anti-ATP7A [L60/4]
Catalogue Number: AB02124-8.4-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | L60/4R; Menke's disease protein; Copper-transporting ATPase 1; Copper pump 1; Menkes disease-associated protein; MC1; MNK |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rat |
| Clone: | L60/4 |
| Isotype: | IgG2b |
| Immunogen: | This antibody was raised by immunising BALB/c mice with a synthetic peptide corresponding to the cytoplasmic N-terminus (amino acids 42-61) of human ATP7A. |
| Application: | IP, IHC, IB |
Additional Text
Gene ID
538
Gene Name
ATP7A
Uniprot ID
Q04656
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody has been used in immunoblot analysis of lysates from human skin fibroblasts, where it recognises a single band (Comstra et al, 2017). This band is missing in ATP7A null human Menkes fibroblasts. It has also been used in immunohistochemical analysis of adult rat hippocampus sections (Andrews et al, 2019; PMID:30667360).
Short Description
This chimeric Rat antibody was made using the variable domain sequences of the original mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
AB02124-8.4 Datasheet
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