Anti-Pan-Nav1 Na+ channel [N419/78]

Catalogue Number: AB02184-10.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:N419/78R; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Sodium channel protein type I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; SCN1A
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: N419/78
Isotype: IgG1
Immunogen: This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 1501-1518 (TEEQKKYYNAMKKLGSKK, cytoplasmic loop between repeat III and IV) of human Nav1.1.
Application: ICC, WB, IHC

Additional Text

Uniprot ID

P35498

Gene ID

6323

Gene Name

SCN1A

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody is recommended for detection and analysis of Nav1 Na+ channel by immunocytochemistry, immunohistochemistry and western blot. For instance, the mouse version of this antibody was used to detect nav1 Na+ channel by western blot in fractions of adult rat brain membranes and extracts of COS or HEK cells transiently or stably expressing different untagged Nav1.X or Kv2.1 plasmid.

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.