Anti-Monkeypox Virus [VACV-5C7]

Catalogue Number: AB02217-12.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Mpox; MPXV; MPXV Cph; Monkeypox virus Copenhagen; VACV-5C7 05.11.20; Anti-ECTV-5C7/1F7; ECTV-5C7/1F7
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: VACV-5C7
Isotype: IgG3
Immunogen: The original mouse IgG1 version of this antibody was raised against sucrose-gradient purified monkeypox virus Copenhagen (MPXV Cph).
Application: ELISA, IF

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Application Notes

This antibody can be used to identify and analyse Monkypox virus (MPV). This clone was used to identify monkypox virus via ELISA (Czerny et al., 1994; pmid: 7513922). VACV-5C7 can be used to develop diagnostic assays which could allow for the detection of orthopox viruses, especially monkypox virus. In Q3 of 2024, the WHO declared monkeypox a Public Health Emergency of International Concern. This product serves as a powerful tool for related research efforts.