Anti-HIV-1 gp120 [694-D]
Catalogue Number: AB02225-10.3-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Envelope glycoprotein; Envelope glycoprotein gp160; Env polyprotein; Surface protein gp120; SU; Glycoprotein 120; 694/98-D; 694/98; 694.8; 694/98D; 694-98D |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | 694-D |
| Isotype: | IgG1 |
| Immunogen: | The original version of this antibody was raised by Epstein-Bar virus (EBV) transformation of peripheral blood mononuclear cells obtained from HIV-infected subjects followed by fusion with the SHM-D33 heteromyeloma (Buchbinder et al., 1992; pmid: 1466965). |
| Application: | ELISA, IF, WB, FA, NT |
Additional Text
Gene ID
155971
Purification
Purified
Uniprot ID
P04578
Antibody Clonality
Recombinant Monoclonal
Gene Name
env
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody was demonstrated to be neutralizing against HIV (Buchbinder et al., 1992; pmid: 1466965). It can be used synergistically with other neutralizing HIV antibodies (such as 447-D). This clone inhibits the binding of gp120 to soluble recombinant CD4 (Buchbinder et al., 1992; pmid: 1466965). Consequently, this antibody is recommended for research on the develpment of successful treatment and prevention of HIV infection, as effective neutralizing antibodies are capable of depleting the viral load in patients exposed to the virus.
AB02225-10.3 Datasheet
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