Anti-BK beta4 K+ channel [L18A/3R]

Catalogue Number: AB02280-10.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Calcium-activated potassium channel subunit beta-4; Kcnmb4; BK channel subunit beta-4; BKbeta4; Calcium-activated potassium channel, subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; K(VCA)beta-4; Maxi K channel subunit beta-4; Slo-beta-4
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Human
Clone: L18A/3R
Isotype: IgG1
Immunogen: This antibody was raised by immunizing a mouse with fusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4.
Application: IF, WB

Additional Text

Gene Name

KCNMB4

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Gene ID

58802

Uniprot ID

Q9JIN6

Application Notes

This antibody was used for immunoblotting on brain tissue from rats exposed to CVS and mouse hippocampi (Yu et al, 2018; PMID:30271963). Immunofluorescence was preformed on HEK293 cells and N2a neurons with this antibody (Chen et al, 2013; PMID:23504458). Transfected HEK293 cells were immunoblotted with this antibody (Chen et al, 2013; PMID:23504458). The hippocampi of rats were immunostained with this antibody. This assay was preformed in order to assess the integrity of mossy fiber pathway and whether MaxiK channel are expressed at mossy fiber axon and terminals (Cox et al, 2014; PMID:24486049). DRG (L4/L5) from rats was used for a western blot with this antibody (Zhang et al, 2012; PMID:22607137).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.