Anti-NKG2D [CX-5]

Catalogue Number: AB02365-6.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:CD314; KLRK1; NKG2-D type II integral membrane protein; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D-activating NK receptor; CX5
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Rat
Clone: CX-5
Isotype: IgG1
Immunogen: The original rat IgG1 version of this antibody was raised by immunizing rats against mouse KLRK1.
Application: FC, NT, Blk

Additional Text

Gene Name

KLRK1

Gene ID

27007

Purification

Purified

Uniprot ID

O54709

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

It has been shown that CX5 is a non-depleting antibody, which blocks binding of NKG2D to its ligands and mediates internalization of the receptor. This antibody has been widely used to block NKG2D (Wang et al., 2018; pmid: 29447423; Yang et al., 2017; pmid: 28455530) as well as to detect NKG2D-posotive cells via flow cytometry (Hosomi et al., 2017; pmid: 28747426).