Anti-SARS-CoV-2 nucleocapsid [mBG86]

Catalogue Number: AB02383-49.0-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	NP; nucleoprotein; NC; Protein N; Nucleocapsid protein; SARS-CoV-2 Protein N; SARS-CoV-2 Nucleocapsid protein; SARS Coronavirus; SARS-CoV-2; SARS CoV 2; 2019-nCoV; 86
Shipping Condition:	Blue Ice
Unit(s):	50 ug
Host name:	Ferret
Clone:	mBG86
Isotype:	IgM
Immunogen:	The original mouse IgG1 version of this antibody was raised by immunizing BALB/c mice with a recombinant SARS-Cov-2 N protein corresponding to AA133-419.
Application:	ELISA, IF, WB

Overview
Datasheets

Additional Text

Gene Name

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Gene ID

43740575

Uniprot ID

P0DTC9

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

Specificty of the original mouse IgG1 version of this antibody to SARS-CoV-2 was confirmed by ELISA (Terry et al., 2021; pmid: 33714753). mBG86 is a particularly useful antibody as it can be used to detect SARS-Cov-2 N protein and differentiate it from SARS-CoV. Western blot analysis demonstrated that this antibody exhibits two band labeling, suggesting a specificity for conformational epitopes on the N protein (Terry et al., 2021; pmid: 33714753). This antibody was shown to detect SARS-CoV-2 N protein in methanol-stained Vero cells by immunofluorescence (Terry et al., 2021; pmid: 33714753). Finally, the original version of mBG86 was demonstrated to be an effective detection antibody in a sandwich ELISA assay suggesting it's potential use in SARS-Cov-2 diagnostics (Terry et al., 2021; pmid: 33714753).

Short Description

This chimeric ferret antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB02383-49.0 Datasheet

Price

£525.00

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