Anti-iC3b [6G1]
Catalogue Number: AB02401-10.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | inactivated C3b; Complement C3; C3; Complement C3 beta chain |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Human |
| Clone: | 6G1 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by immunizing mice intraperitoneally with human iC3b protein mixed with RIBI adjuvant. |
| Application: | ELISA, IP, IHC |
Additional Text
Gene Name
C3
Gene ID
718
Uniprot ID
P01024
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody binds iC3b with a dissociation constant of 43.3 nM. This antibody can be used in combination with 5D2 to detect iC3b in a sanwich ELISA. This antibody was used to identify iC3b using immunoprecipitation. This antbody was also used for the immunohistochemical analysis of Alzheimer's disease brain and was successful in labelling plaques with various morphologies in the grey matter at a 0.625 µg/mL dilution. This antibody can successfully stain human bruch's membrane/choroid tissues samples from patients having age related macular degeneration (AMD). It was able to identify drusen associated with bruch's membrane in stage 3 and 4 AMD tissues (US20140127225).
Short Description
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB02401-10.0-BT Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations