Anti-4-1BB [BBK2]
Catalogue Number: AB02445-10.3-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | CD137; MGC2172; Tumor necrosis factor receptor superfamily member 9; TNFRSF9; T cell antigen ILA; Interleukin activated receptor; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; BBK-2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | BBK2 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was raised by immunizing a mouse with CD137. |
| Application: | FC, IF, IP, IHC, Blk, Ant |
Additional Text
Gene ID
3604
Gene Name
TNFRSF9
Uniprot ID
Q07011
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
An in vitro T cell killing assay was performed using this antibody (US20200407440). Immunofluorescence was performed on KM-H2 cells using this antibody (Ho et al, 2013; pmid:23204227). Flow cytometry was performed with this antibody on cell lines: KM-H2, L-428, L-1236 KM-H2-control, KM-H2-CD137 and stable cell lines expressing CD137 or CD137L (Ho et al, 2013; pmid:23204227). Immunoprecipitation was performed with this antibody on the cell lines: KM-H2, L-428, L-1236 KM-H2-control, KM-H2-CD137 and stable cell lines expressing CD137 or CD137L (Ho et al, 2013; pmid:23204227). This antibody was used for immunohistochemistry on human tissue from lung, liver, colon, soft tissue, thyroid gland, stomach, parathyroid gland, and spleen, parotid gland, heart, aorta, kidney, and lymph node (Broll et al, 2001; pmid:11293902). Human lymph node was used for immunohistochemistry using this antibody (Pauly et al, 2002; pmid:12101260). Flow cytometry was performed on cell line FDC-H1, Human peripheral blood mononuclear cells and B lymphocytes using this antibody (Pauly et al, 2002; pmid:12101260). This antibody was used for immunohistochemistry on human tissue (Drenkard et al, 2007; pmid:17167064). Blocking of the CD137-fc protein was tested in MoDC cells using this antibody (Lippert et al, 2008; pmid:18395851).
Short Description
This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB02445-10.3 Datasheet
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