Anti-4-1BB [BBK4 ]

Catalogue Number: AB02446-23.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:CD137; MGC2172; Tumor necrosis factor receptor superfamily member 9; TNFRSF9; T cell antigen ILA; Interleukin activated receptor; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; BBK-4
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Rabbit
Clone: BBK4
Isotype: IgG
Immunogen: The original antibody was raised by immunizing a mouse with CD137.
Application: ELISA, FC, Agon

Additional Text

Gene ID

3604

Gene Name

TNFRSF9

Uniprot ID

Q07011

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody stimulates T-cell activity (Son et al, 2004; pmid:15087232). ELISA was performed using this antibody on E.coli expressed human 4-1BB (Son et al, 2004; pmid:15087232). Mixed lymphocyte reaction was investigated with fresh peripheral blood mononuclear cells using this antibody (Son et al, 2004; pmid:15087232). This antibody was used for flow cytometry on a subline of human Jurkat 8-1 cells (Son et al, 2004; pmid:15087232). This antibody promoted long-term proliferation of PBMC (Son et al, 2004; pmid:15087232).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.