Anti-FGRI [M5G10]
Catalogue Number: AB02532-6.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Fibroblast growth factor receptor 1; FGFR-1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD331 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rat |
| Clone: | M5G10 |
| Isotype: | IgG1 |
| Immunogen: | Balb/c mice were immunized with recombinant human FGF-R1a or with both recombinant human FGF-R1b and recombinant human FGF-R1a . |
| Application: | IP, WB, RIA, IHC |
Additional Text
Gene Name
FGFR1
Gene ID
2260
Uniprot ID
P11362
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
To characterize this antibody a western blot was preformed on sf9 cells transfected with baculovirus recombinantly expressing the full length FGF-R1 protein. Furthermore immunoprecipitation was preformed on the lysed sf9 cells transfected with baculovirus recombinantly expressing the full length FGF-R1 protein. And finally a radioimmunityassay was preformed with the mouse version of this antibody on I125-labeled complexes (Xu et al, 1992; pmid:1325449). The distribution of FGF-1, FGF-2, and FGFR-1 was analysed using immunohistochemistry on tissue specimens of malignant salivary gland tumours using the mouse version of this antibody (Myoken et al, 1996; pmid:8691322). The mouse version of this antibody was used to immunoprecipitate lysed TRAMP-C2 cells. This was done to understand how FRS2 interacted with FGFR1 (Zhang et al, 2008; pmid:17901128).
Short Description
This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB02532-6.1 Datasheet
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