Anti-CD56 ANK-1 [8G6]

Catalogue Number: AB02588-1.1-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Alias:	CD56; ANK1; NCAM1; NCAM-1; N-CAM-1; Ncam; Neural cell adhesion molecule 1
Shipping Condition:	Blue Ice
Unit(s):	0.1 mg
Host name:	Mouse
Clone:	8G6
Isotype:	IgG1
Immunogen:	The original antibody was generated by immunizing rats with purified mouse brain N-CAM.
Application:	FC, IHC-P, WB

Overview
Datasheets

Additional Text

Gene Name

NCAM1

Uniprot ID

P13595

Gene ID

17967

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody was used to classify the nonactivated human peripheral blood NK cells expressing ANK-1 epitope using flow cytometry. It was reported that ANK-1 epitope was preferentially expressed by around 26% of NK cells (range 9-56%) and was exclusively CD56dim. This antibody was also capable of detecting ANK-1 epitope from crude human peripheral blood NK cell and affinity purified brain N-CAM lysates using western blot. This antibody was also used to test the ability of NK cells to respond to IL-2 by generation and expansion of A-NK cells with LAK activity, following depletion of ANK-1+ NK cells by treatment with mAb ANK-1 and complement. This antibody can also be used for the immunohistochemical staining of paraformaldehyde fixed paraffin embedded tissues of spleen, lymph nodes, tonsils, intestines, lungs, and liver tissues (PMID: 15356097).

Short Description

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgM format, for improved compatibility with existing reagents, assays and techniques.

AB02588-1.1 Datasheet

Price

£430.00

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