Anti-CD127 [6A3]

Catalogue Number: AB02641-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:IL7R; IL7Rα; IL-7Rα; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R-alpha; IL-7RA; CDw127
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: 6A3
Isotype: IgG
Immunogen: The original antibody was generated by immunizing Balb/c mice with dimeric recombinant human CD127 extracellular domain.
Application: ELISA, WB, IHC, NT, SPR, Ant

Additional Text

Gene ID

3575

Uniprot ID

P16871

Gene Name

IL7R

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

ELISA was performed on CD127 using this antibody (WO2010017468). This antibody was tested for inhibition of IL-7 induced IFN-γ and IL-17 in a TH17 expansion assay (WO2010017468). Flow cytometry was performed on Mock transfected CHO or CHO-CD127 cells using this antibody (WO2010017468). Surface plasmon resonance was performed with this antibody on CD127 to test the binding affinity (WO2010017468). Immunohistochemistry was performed on the spinal cord of a mouse using this antibody (WO2010017468). A neutralizing assay was performed on CD127 protein using this antibody (WO2010017468). Western blot was performed on protein extract using this antibody (WO2010017468).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.