Anti-CRIPTO protein [B3F6]

Catalogue Number: AB02648-10.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Cryptic protein; CFC1; Cryptic family protein 1
Shipping Condition:Blue Ice
Unit(s): 200 ug
Host name: Human
Clone: B3F6
Isotype: IgG1
Immunogen: The original antibody was generated by immunizing mice with a Cripto fusion protein expressed in CHO cells. The fusion protein comprise of amino acid residues 1 to 169 of Cripto, fused to a human IgG1 Fc domain. The humanized version was synthetically constructed by grafting the CDRs of the original mouse version onto variable region framework residues substantially from a human antibody chain.
Application: FC, Blk

Additional Text

Gene ID

55997

Gene Name

CFC1

Uniprot ID

P0CG37

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

Flow cytometry was performed on GEO cells using this antibody (US8021661). It was assessed whether this antibody could inhibit BT-474 tumor growth in mice (US8021661). It was assessed whether this antibody could inhibit the growth of CLAU-6 human lung cancer cells in mice (US8021661).