Anti-CRIPTO protein [B3F6]
Catalogue Number: AB02648-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Cryptic protein; CFC1; Cryptic family protein 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rabbit |
| Clone: | B3F6 |
| Isotype: | IgG |
| Immunogen: | The original antibody was generated by immunizing mice with a Cripto fusion protein expressed in CHO cells. The fusion protein comprise of amino acid residues 1 to 169 of Cripto, fused to a human IgG1 Fc domain. The humanized version was synthetically constructed by grafting the CDRs of the original mouse version onto variable region framework residues substantially from a human antibody chain. |
| Application: | FC, Blk |
Additional Text
Gene ID
55997
Gene Name
CFC1
Uniprot ID
P0CG37
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
Flow cytometry was performed on GEO cells using this antibody (US8021661). It was assessed whether this antibody could inhibit BT-474 tumor growth in mice (US8021661). It was assessed whether this antibody could inhibit the growth of CLAU-6 human lung cancer cells in mice (US8021661).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB02648-23.0 Datasheet
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