Anti-DLL4 [61B]
Catalogue Number: AB02657-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Delta-like protein 4; Drosophila Delta homolog 4; Delta4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Rabbit |
| Clone: | 61B |
| Isotype: | IgG |
| Immunogen: | The original antibody was generated by immunizing mice with soluble human Dll4-His protein. |
| Application: | ELISA, IF, IHC, Blk |
Additional Text
Gene ID
54567
Gene Name
DLL4
Uniprot ID
Q9NR61
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
U87MG and HT29 cells were immune-stained with this antibody (Zhou et al, 2015; pmid:26288060). This antibody is used for immunohistochemistry on U87MG and HT29 (Zhou et al, 2015; pmid:26288060). The 64Cu-chelator DOTA conjugated version of this antibody was used for the positron-emission tomography (PET) imaging of human glioblastoma and colorectal cancer xenografts (Zhou et al, 2015; pmid:26288060). This antibody was used for immunohistochemistry on spheroids and monolayers cells (US7906116). ELISA was performed with this antibody on Dll4 truncation mutants (US7906116). This antibody is able to block the Dll4-Notch1 interaction (US7906116).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
AB02657-23.0 Datasheet
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