Anti-Spike protein [18F4]

Catalogue Number: AB02741-12.1-BT-ABA

Manufacturer:	Vector Laboratories, Inc (ABA)
Type:	Recombinant Monoclonal
Shipping Condition:	Blue Ice
Unit(s):	1 mg
Host name:	Human
Clone:	18F4
Isotype:	IgG3
Immunogen:	This antibody was raised by immunizing DivergimAb mice with SARS CoV2 spike protein S1 subunit.
Application:	ELISA, FA, Blk, SPR

Overview
Datasheets

Additional Text

Gene Name

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Gene ID

43740568

Uniprot ID

P0DTC2

Specificity

SARS CoV 2 S glycoprotein; COVID-19 Spike protein; RBD; Receptor Binding Domain; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

To characterize this antibody, an indirect ELISA was performed using the mouse version of this antibody. The antigen used was the SARS CoV2 spike protein. The mouse version of this antibody is capable of binding the S1 protein and blocking S1:ACE2 interaction. This antibody is reported to bind non-competitively with another anti-SARS CoV2 antibody D70678-5521-S2. Further, both biolayer interferometry and surface plasmon resonance were used to determine the kinetics of the mouse version of this antibody. Both experiments used the SARS CoV2 spike protein as the antigen (Mullen et al, 2021).

Short Description

This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

AB02741-12.1-BT Datasheet

Price

£1,655.00

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