Catalogue Number: AB02743-10.3-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Human |
| Clone: | 4A8 |
| Isotype: | IgG1 |
| Immunogen: | This antibody was isolated from the blood of recovered SARS CoV2 patients. |
| Application: | ELISA, FC, FA, NT |
S
Purified
Recombinant Monoclonal
43740568
P0DTC2
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
The binding profile of this antibody was determined by performing an ELISA on SARS-CoV-2 S, S1, S2 or RBD protein using the human version of this antibody. Furthermore a neutralization experiment on Vero-E6 cells infected with SARS CoV2 was done using the human IgG1 version of this antibody. The binding of the human version was also characterized using biolayer interferometry. A flow cytometric receptor binding inhibition assay was also performed on the human version of this antibody incubated in SARS-CoV-2S protein and then incubated with ACE2-293T cells. The complex of S-ECD and the human version of this antibody was characterized using cryo electromicroscopy (Chi et al, 2020; pmid:32571838).
SARS CoV 2 S glycoprotein; COVID-19 Spike protein; E2 glycoprotein; E2; Human coronavirus 2 spike glycoprotein; Peplomer protein; S glycoprotein; SARS coronavirus 2 S protein; SARS coronavirus 2 Spike Protein; SARS CoV 2 Spike protein; SARS CoV 2; SARS-CoV-2 S protein; SARSCoV2; SARS-COV-2 S protein; SARS-COV-2 Spike glycoprotein; SARSCOV2 Spike protein; Severe acute respiratory syndrome 2 spike glycoprotein; Severe acute respiratory syndrome virus 2 spike glycoprotein; Spike glycoprotein; 2019-nCoV