Anti-CD56 [NKINBL1]
Catalogue Number: AB02880-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | NKI-NBL-1; Neural cell adhesion molecule 1; NCAM1; N-CAM-1; NCAM-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | NKINBL1 |
| Isotype: | IgG |
| Immunogen: | The mouse version of this antibody was raised by immunizing a BALB/c mouse with CHP-212 human neurablastoma cell line. |
| Application: | FC, WB, IHC, Depl |
Additional Text
Gene Name
NCAM1
Gene ID
4684
Uniprot ID
P13591
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
To quantify CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages, flow cytometry was performed on multiple human cell lines using the mouse version of this antibody (Lee et al, 1999; pmid:10220446). To determine differences in the expression level of selected adhesion molecules to identify suitable tools for the pre-procedural identification of restenosis patients before angioplasty, flow cytometry was performed on PMBCs using the mouse version of this antibody (Rahimi et al, 2003; pmid:12717693). To test the ability of OM-174 to stimulate in vitro the lytic potential of peripheral blood cells from patients with non-metastatic breast tumour, the mouse version of this antibody was used for NK depletion on mononuclear blood cells (Reisser et al, 1999). The mouse version of this antibody was used in whole full blood for flow cytometry to characterize the coreceptor activity and the expression pattern of alternative coreceptors that are used by HIV-1 to enter the cell (Sharron et al, 2000; pmid:10891428). To determine the specificity of the mouse version of the antibody, a western blot was performed on different CD56 isoforms. This antibody showed no specificity for any isoform (Gattenloehner et al, 2009; pmid:19246644). To study tumour infiltrating dendritic cells, Tissue samples collected at the time of nephrectomy were used for immunohistochemistry using the mouse version of this antibody (Schwaab et al, 1999; pmid:10411089).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
AB02880-23.0-BT Datasheet
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