Anti-15-acetyl-deoxynivalenol [NAT-267]

Catalogue Number: AB02929-23.159-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:15-AcDON; DON; Mycotoxin; Deoxynivalenol; Vomitoxin, Fusarium mycotoxin; mNAT-267; NAT-267; ChEBI: 10022
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: NAT-267
Isotype: IgG
Immunogen: The original antibody was generated by immunization of a llama (Llama glama) with the protein conjugate 15-DON-BSA in a TiterMax Classic adjuvant.
Application: ELISA, SPR

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody can bind 15-AcDON in a competitive direct enzyme-linked immunosorbent assay (CD-ELISA) and fluorescence polarization assay (FPA). This antibody does not cross react with DON; 3-acetyldeoxynivalenol (3-AcDON); neosolaniol (NEO); diacetoxyscirpenol (DAS); and T-2 toxin. Surface plasmon resonance (SPR) analysis of soluble NAT-267 binding kinetics to immobilized 15-DON-Horse Radish Peroxidase (HRP) indicated a dissociation constant KD of 5microM (PMID: 18632156).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original VHH format for improved compatibility with existing reagents assays and techniques.