Anti-Phospho-Tau [pT231/pS235_1]
Catalogue Number: AB02979-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | MAPT; TAU; PHF-tau; PHF; MAPTL; MTBT1; Tau proteins; Phospho-Tau (pT231/pS235); Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | pT231/pS235_1 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | ELISA, IHC, SPR |
Additional Text
Gene Name
MAPT
Gene ID
4137
Uniprot ID
P10636
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
ELISA was used for the screening of positive clones that bind phosphopeptides. The binding affinity of the IgG antibody towards pT231/pS235 phosphopeptide was found to be Kd = 0.35 nM using surface plasmon resonance. This antibody can recognize the phospho-tau epitopes in full-length human tau. This antibody was also used for the immunohistochemical analysis of the human brain with Alzheimer's disease (PMID: 23148212).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Chicken scFv format for improved compatibility with existing reagents, assays, and techniques.
AB02979-23.0-BT Datasheet
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