Anti-Norovirus GII.10 [5B18]
Catalogue Number: AB03162-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | capsid protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Mouse |
| Clone: | 5B18 |
| Isotype: | IgG1 |
| Immunogen: | The antibody was generated from a mouse immunized with GII.4 norovirus-445 VLPs. |
| Application: | ELISA, IF, WB, Crstion |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
UniProt ID
Q5F4T5
Application Notes
The specificity of the IgG format of this antibody was confirmed by ELISA analysis; the antibody detected intact GII.10 VLPs at different pH values with nearly identical efficacy. The structure of the Fab fragment in complex with GII.10 P domain was determined. The Western blotting results showed that the antibody IgG could detect the three GII genotypes (Hansman et al., 2012; PMID: 22278249). The antibody was used for immunofluorescence microscopy to examine VLP binding to fresh biopsies of human ileum and it bound specifically to VLPs (Murakami et al., 2013; PMID: 23799113).
Short Description
This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format for improved compatibility with existing reagents assays and techniques.
AB03162-1.1 Datasheet
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