Anti-Histone H4 [1A9D7]

Catalogue Number: AB03227-1.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:H4K5acK8ac; Histone H4 protein
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Mouse
Clone: 1A9D7
Isotype: IgG1
Immunogen: The original antibody was generated by immunizing mice with Histone H4 protein with site-specific acetylations at K5 and K8.
Application: ELISA, WB, Crstion

Additional Text

Uniprot ID

P62805

Purification

Purified

Gene ID

121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370

Antibody Clonality

Recombinant Monoclonal

Gene Name

H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The specificity of the original format of the antibody for histone H4 proteins containing di-acetylation of K5acK8ac was confirmed by ELISA analysis. The antibody detected the histone H4 proteins containing at least the di-acetylation of K5acK8ac western blot analysis. The crystal structure of the complex of di-acetylated histone H4 and 1A9D7 Fab fragment was determined (Handoko et al., 2018; PMID: 30080437).

Short Description

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format for improved compatibility with existing reagents assays and techniques.