Anti-FcRn [h22-0015]
Catalogue Number: AB03237-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | IgG receptor FcRn large subunit p51; FCGRT; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Mouse |
| Clone: | h22-0015 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by immunizing Balb/c mice with recombinant FcRn. |
| Application: | Blk, InVitroA, InVivoA |
Additional Text
Gene Name
FCGRT
Uniprot ID
P55899
Gene ID
2217
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
The antibody was employed in blocking experiments with HEK293 cells that overexpress FcRn. The results showed that the antibody has a good effect of blocking the binding of IgG to FcRn at the cellular level (IC50: 11.4nM). The effect of the antibody was tested in human FcRn transgenic mice. The antibody was able to increase IgG catabolism in vivo by blocking FcRn binding (CN113484526).
AB03237-1.1 Datasheet
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