Anti-MOG [8.18-C5]
Catalogue Number: AB03388-23.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Myelin-oligodendrocyte glycoprotein; 8.18C5; 8-18C5 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Rabbit |
| Clone: | 8.18-C5 |
| Isotype: | IgG |
| Immunogen: | The original antibody was generated immunizing mice against Thy-1-depleted rat cerebellar glycoproteins. |
| Application: | ELISA, FC, IF, WB, IHC, InVivoA, Crstion |
Additional Text
UniProt ID
Q63345
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody was detected in white matter tracts of the central nervous system by immununohistochemistry. The antibody detected MOG by western blot analysis (Linnington et al., 1984; PMID: 6207204). The specificity of the original format of the antibody and Fab fragment was confirmed by ELISA analysis (Litzenburger et al., 1998; PMID: 9653093 and Menge et al., 2011; PMID: 22093619). This antibody was used for detection of MOG expressed on B cells by flow cytometry (Na et al., 2021; PMID: 34149706). MOG from HeLa cells were immunoprecipitated with the antibody. Immunofluorescence was performed on HeLa cells using this antibody (Boyle et al., 2007; PMID: 17573820). The antibody triggered in vivo expansion of CD4+ T cells in spleen, inguinal, and cervical lymph nodes (Kinzel et al. 2016; PMID: 27022743). The crystal structure of the Fab version of this antibody was determined in complex with MOGIgd (Breithaupt et al., 2003; PMID: 12874380).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
AB03388-23.0-BT Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations