Anti-CCL20 [AB1]

Catalogue Number: AB03417-10.3-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:C-C motif chemokine 20; Beta-chemokine exodus-1; CC chemokine LARC; CC chemokine ST38; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha; Small-inducible cytokine A20
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Human
Clone: AB1
Isotype: IgG1
Immunogen:
Application: ELISA, InVitroA, SPR

Additional Text

Uniprot ID

O89093

Gene Name

CCL20

Gene ID

20297

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The specificity of the original format of the antibody was confirmed by ELISA analysis. Capture ELISA was performed and the 1:1 binding kinetics and affinities were measured by surface plasmon resonance (Kd= 2.3 nM). CCR6 Chinese hamster ovary (CHO)-K1 β-arrestin G protein-coupled receptor functional assay was performed to measure the inhibition of the antibody (IC50= 30.7).

Short Description

This chimeric human antibody was made using the variable domain sequences of the original Mouse Fab format for improved compatibility with existing reagents assays and techniques.