Anti-CCR2 [4.9]
Catalogue Number: AB03418-3.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | CD192; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CMKBR2; 4.9.2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
| Host name: | Mouse |
| Clone: | 4.9 |
| Isotype: | IgG2b |
| Immunogen: | The original antibody was generated by immunizing human immunoglobulin generating XENOMOUSE™ mice with human CCR2 antigen. |
| Application: | ELISA, FC, Ant |
Additional Text
Gene ID
729230
Gene Name
CCR2
Uniprot ID
P41597
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
The binding specificity of this antibody to full length CCR2, and 1St and 2nd loop of CCR2 was determined using ELISA. The binding reactivity of this antibody to the surface bound CCR2 receptors was confirmed with flow cytometry. This antibody can positively inhibit chemotaxis of THP-1 monocytes. The therapeutic effects of this antibody were studied in in vivo mouse models of inflammation, multiple sclerosis and neuropathic pain (US8710191).
Short Description
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.
AB03418-3.0-BT Datasheet
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