Anti-CPS-500 [18.44]
Catalogue Number: AB03424-21.0-BT-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | β-mannosylated glycolipid, CPS-500 antigen |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ug |
| Host name: | Mouse |
| Clone: | 18.44 |
| Isotype: | IgM |
| Immunogen: | The original antibody was generated by immunizing mice with whole cells of Cryptosporidium parvum. |
| Application: | ELISA, IF, EM, WB |
Additional Text
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody reacts with both sporozoites and merozoites of C. parvum in an indirect immunofluorescence assay. This antibody is capable of neutralizing sporozoites and merozoites in a time dependent manner (PMID: 2193057; 2473130). This antibody can be used for the identification of sporozoites, merozoites and CPS-500 antigen of C. parvum using western blot. The identification of sporozoite-neutralizing antibody was done using ELISA (PMID: 20086143). This antibody in combination with PLA2 or LL37 was also used in the generation of a biocide fusion proteins to kill C. parvum sporozoites in vitro and in vivo (PMID: 20086143).
Short Description
This reformatted mouse antibody was made using the variable domain sequences of the original mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
AB03424-21.0-BT Datasheet
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