Anti-CD277 [108.5]

Catalogue Number: AB03874-1.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:BTN3A1; BTF5; BT3; BT3.1; Butyrophilin subfamily 3 member A1
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: 108.5
Isotype: IgG1
Immunogen: The original antibody was generated by immunizing BALB/c mice with soluble BT3.1-Ig fusion protein.
Application: FA, Ant

Additional Text

Gene ID

11119

Gene Name

BTN3A1

Uniprot ID

O00481

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody was used as an antagonist antibody to check if BTN3A can specifically enhance Vg9Vd2 TCR-mediated lysis of primary AML blasts using cytotoxic assays. This antibody was reported to significantly and drastically abrogate zoledronate (ZOL)-induced lysis (PMID: 27853633). This antibody can completely abrogate Vγ9Vδ2 T cell mediated lysis of tumors (PMID: 29296524).