Anti-CD277 [108.5]
Catalogue Number: AB03874-23.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | BTN3A1; BTF5; BT3; BT3.1; Butyrophilin subfamily 3 member A1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Rabbit |
| Clone: | 108.5 |
| Isotype: | IgG |
| Immunogen: | The original antibody was generated by immunizing BALB/c mice with soluble BT3.1-Ig fusion protein. |
| Application: | FA, Ant |
Additional Text
Gene ID
11119
Gene Name
BTN3A1
Uniprot ID
O00481
Purification
Purified
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody was used as an antagonist antibody to check if BTN3A can specifically enhance Vg9Vd2 TCR-mediated lysis of primary AML blasts using cytotoxic assays. This antibody was reported to significantly and drastically abrogate zoledronate (ZOL)-induced lysis (PMID: 27853633). This antibody can completely abrogate Vγ9Vδ2 T cell mediated lysis of tumors (PMID: 29296524).
Short Description
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
AB03874-23.0 Datasheet
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