Anti-M protein, serotype 5 [27.4.1]

Catalogue Number: AB03910-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Myosin; Streptococcal M-protein; Keratin; Tropomyosin; Ganglioside; Glycophorin M,N
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 1 mg
Host name: Rabbit
Clone: 27.4.1
Isotype: IgG
Immunogen: The original antibody was generated by immunizing BALB/c mice with streptococcal M type 5 membranes followed by a second, boosting dose of Lysin M5.
Application: ELISA, IF, HA

Additional Text

Purification

Purified

Uniprot ID

P02977

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody reacts with the human retina, as shown in an indirect immunofluorescence assay. This antibody reacts with retinal S-antigen (S-Ag), as shown in an ELISA (Lerner et al., 1995; PMID: 8722579). This antibody binds myosin at a high relative avidity, as determined in a competitive ELISA. Reactivity with glycophorin M and N was determined by hemagglutination assay (Mertens et al., 2000; PMID: 11282394).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.