Anti-M protein, serotype 5 [54.2.8]
Catalogue Number: AB03918-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | M protein, serotype 6; M protein, serotype 12; Myosin; Streptococcal M-protein; Keratin; DNA; Vimentin; Tropomyosin; Troponin; Ganglioside; Glycophorin M,N |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Mouse |
| Clone: | 54.2.8 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was generated by immunizing BALB/c BYJ mice with streptococcal M type 5 membranes followed by a second, boosting dose of M type 5 streptococcal membranes. |
| Application: | ELISA, IF, WB, HA, PRNT |
Additional Text
Purification
Purified
Uniprot ID
P02977
Antibody Clonality
Recombinant Monoclonal
Storage Note
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Application Notes
This antibody reacts with rabbit myosin, as shown in a WB. This antibody reacts with M type 5 membrane proteins and human heart cell extract, as shown in an ELISA (Krisher et al., 1985; PMID: 2578225). This antibody reacts with the heavy chain of cardiac myosin. Specifically, it reacts with both heavy and light meromyosin fragments, as shown in WB and competitive inhibition assays (Cunningham et al., 1986; PMID: 3510006). This antibody stains the nuclei and cytoplasm of cells within the epidermis and epidermal appendages, as well as cells scattered throughout the dermis in normal and psoriatic skin, as shown by immunofluorescent staining (Swerlick et al., 1986; PMID: 3525693). This antibody binds CV (B3), as shown in an ELISA; neutralizes PV-1 and CV (B3), as shown in a plaque-reduction neutralization assay; and is moderately cytotoxic to rat fibroblasts, as shown in a cytotoxicity assay (Cunningham et al., 1992; PMID: 1311095). This antibody reacted with retinal S-antigen (S-Ag) in an ELISA (Lerner et al., 1995; PMID: 8722579). This antibody binds myosin at a high relative avidity, as determined in a competitive ELISA. Reactivity with glycophorin M and N was determined by hemagglutination assay (Mertens et al., 2000; PMID: 11282394).
AB03918-1.1 Datasheet
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