Anti-D-Dimer [MA-15C5]

Catalogue Number: AB03954-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:XDP; Fragment D-dimer; Fibrin degradation fragment; Fibrin degradation product; Fibrin
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: MA-15C5
Isotype: IgG
Immunogen: The original antibody was generated by immunizing BALB/c mice with purified fragment D-dimer from cross linked human fibrin.
Application: ELISA, Img

Additional Text

Gene ID

2243

Uniprot ID

P02671

Gene Name

FGA

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

This antibody has a 1000 fold higher affinity for binding human fragment D-dimer than for human fibrinogen. It could effectively bind D-dimer from human plasma clots and can be used for thrombus imaging in an animal model in vivo (PMID: 2749602). This antibody has been used in an ELISA assay for the quantification of fragment-D dimer in plasma (PMID: 3127914).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.