Anti-HLA class I [F17B1]

Catalogue Number: AB03964-1.1-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Mouse
Clone: F17B1
Isotype: IgG1
Immunogen: The original antibody was generated by immunizing male MRL/lpr mice with an an emulsion containing complete adjuvant H37Ra and purified sHLA-A-flag protein.
Application: FACS, FC, InVivoA

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The original antibody showed strong cell death-inducing activity by FACS analysis. The antibody was used for detection of beads coated HLA class I antigen by flow cytometry. The human chimeric and the humanized version of the antibody was constructed. The human chimeric antibody was administered into a mouse model for human myeloma. The result showed that the antibody can significantly prolong the survival period of the mouse model for human myeloma.