Anti-DLL4 [H3L2]

Catalogue Number: AB04084-10.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Delta4; Delta-like protein 4; Drosophila Delta homolog 4
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Human
Clone: H3L2
Isotype: IgG1
Immunogen: The original antibody is a humanized version of the parental murine monoclonal antibody.
Application: FC, SPR

Additional Text

Gene ID

54567

Gene Name

DLL4

Uniprot ID

Q9NR61

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The antibody retained the high affinity of the parental murine antibody to human DLL4 antigen (KD = 2.26 pM), as measured by SPR experiments. The humanized antibody bound to the DLL4 antigen on the surface of HUVEC cells, as shown by flow cytometry. Further, the antibody could block the inhibitory effect of DLL4 on the proliferation of HUVEC cells (CN105384819B).