Anti-SN-38 [1H3-1]

Catalogue Number: AB04092-23.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:SN38; Topotecan; Camptothecin; CPT; 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin; 10-Hydroxy-7-ethylcamptothecin; 7-Ethyl-10-hydroxy-20(S)-camptothecin; 7-Ethyl-10-hydroxycamptothecin; NK 012; NK-012
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Rabbit
Clone: 1H3-1
Isotype: IgG
Immunogen: The original antibody was generated by immunizing BALB/c mice with SN38-BSA conjugate.
Application: ELISA, SPR

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The binding reactivity of this antibody to SN38-BSA conjugate was determined using ELISA. The binding affinity of this antibody to SN38-KLH conjugate was determined using surface plasmon resonance (SPR). It was reported that this antibody binds SN38-KLH conjugate with a binding affinity of Kd=3.06 nM (CN115197323).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.