Catalogue Number: AB04108-10.0-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | Glycoprotein 38; Crimean-Congo Hemorrhagic Fever Virus glycoprotein 38; CCHFV GP38; CC5_17 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Human |
| Clone: | CC5-17 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was isolated from donor "CC5", a CCHFV survivor; circulating anti-GP38 antibodies were isolated from plasma using affinity chromatography. The paired heavy and light chain sequences were obtained from proteomics and genomics analyses, and the antibody was produced by transfecting Expi293 cells (expiCHO-S cells) with 1:1 ratio of heavy chain plasmid to light chain plasmid. |
| Application: | ELISA, SPR |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
The binding of this antibody's original format (human IgG1) to GP38 was evaluated using ELISA. It had an association constant (Ka) of 3.9 x 105 M-1s-1 as measured by surface plasmon resonance (SPR) (Durie et al., 2022; PMID: 36435827).