Anti-GP38 [CC5-17]

Catalogue Number: AB04108-10.0-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:Glycoprotein 38; Crimean-Congo Hemorrhagic Fever Virus glycoprotein 38; CCHFV GP38; CC5_17
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Human
Clone: CC5-17
Isotype: IgG1
Immunogen: The original antibody was isolated from donor "CC5", a CCHFV survivor; circulating anti-GP38 antibodies were isolated from plasma using affinity chromatography. The paired heavy and light chain sequences were obtained from proteomics and genomics analyses, and the antibody was produced by transfecting Expi293 cells (expiCHO-S cells) with 1:1 ratio of heavy chain plasmid to light chain plasmid.
Application: ELISA, SPR

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Application Notes

The binding of this antibody's original format (human IgG1) to GP38 was evaluated using ELISA. It had an association constant (Ka) of 3.9 x 105 M-1s-1 as measured by surface plasmon resonance (SPR) (Durie et al., 2022; PMID: 36435827).