Anti-Envelope glycoprotein H and L [94]

Catalogue Number: AB04130-1.1-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:gHgL; gH; gL; envelope glycoprotein H; envelope glycoprotein L; Varicella zoster virus; VZV; human herpesvirus 3; HHV-3; HHV3; Human alpha herpesvirus 3; Chickenpox; VZ94; IgG-94
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: 94
Isotype: IgG1
Immunogen: The original antibody was isolated from a combinatorial library of human antibodies (AIMS4) using a phage-display system by panning the library against purified varicella-zoster virus (VZV) gH:gL complex.
Application: ELISA, IP, NT

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

UniProt ID

Q775J3, Q9J3N1

Application Notes

This antibody reacted with gH and gL in an ELISA. This antibody was also capable of reacting with gH:gL complex and VZV-infected cells. This antibody was used for the immunoperoxidase staining of VZV-infected human embryonic lung (HEL) cells. This antibody neutralized wild strains without showing strain specificity. This antibody was also reported to prevent the spreading of virus infection. This antibody was also capable of immunoprecipitating gH and gL glycoproteins of VZV (PMID: 17457901).

Short Description

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.