Catalogue Number: AB04130-1.1-ABA
| Manufacturer: | Vector Laboratories, Inc (ABA) |
| Type: | Recombinant Monoclonal |
| Alias: | gHgL; gH; gL; envelope glycoprotein H; envelope glycoprotein L; Varicella zoster virus; VZV; human herpesvirus 3; HHV-3; HHV3; Human alpha herpesvirus 3; Chickenpox; VZ94; IgG-94 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | Mouse |
| Clone: | 94 |
| Isotype: | IgG1 |
| Immunogen: | The original antibody was isolated from a combinatorial library of human antibodies (AIMS4) using a phage-display system by panning the library against purified varicella-zoster virus (VZV) gH:gL complex. |
| Application: | ELISA, IP, NT |
Purified
Recombinant Monoclonal
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Q775J3, Q9J3N1
This antibody reacted with gH and gL in an ELISA. This antibody was also capable of reacting with gH:gL complex and VZV-infected cells. This antibody was used for the immunoperoxidase staining of VZV-infected human embryonic lung (HEL) cells. This antibody neutralized wild strains without showing strain specificity. This antibody was also reported to prevent the spreading of virus infection. This antibody was also capable of immunoprecipitating gH and gL glycoproteins of VZV (PMID: 17457901).
This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.