Anti-Envelope glycoprotein H and L [rec-RC-IgG]

Catalogue Number: AB04131-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:gHgL; gH; gL; envelope glycoprotein H; envelope glycoprotein L; Varicella zoster virus; VZV; human herpesvirus 3; HHV-3; HHV3; Human alpha herpesvirus 3; Chickenpox; IgG-RC
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: rec-RC-IgG
Isotype: IgG
Immunogen: The original antibody was isolated from circulating blood plasmablast of a 59-year-old VZV-seropositive man recently immunized with zoster vaccine Zostavax.
Application: IP, IHC, NT

Additional Text

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

UniProt ID

Q775J3, Q9J3N1

Application Notes

This antibody was used for the immunohistochemical staining of fixed and unfixed VZV-infected and control human lung fibroblast cells. This antibody was also reported to neutralize VZV infection in a plaque reduction assay. The concentration of IgG that produced 50% plaque reduction was 0.6 µg/ml. This antibody was also used for the immunoprecipitation of VZV-infected cells (PMID: 23077312).

Short Description

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.