Anti-CD81 [Ab10]

Catalogue Number: AB04212-23.0-BT-ABA

Manufacturer:Vector Laboratories, Inc (ABA)
Type:Recombinant Monoclonal
Alias:CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28 (Tspan-28)
Shipping Condition:Blue Ice
Unit(s): 1 mg
Host name: Rabbit
Clone: Ab10
Isotype: IgG
Immunogen: The original antibody was generated by immunization of Balb/c and Naval Medical Research Institute (NMRI) mice with CD81 extracellular loop 2 (ECL2) protein.
Application: FACS, FC, Inh, Crstion

Additional Text

Gene Name

CD81

Gene ID

975

Uniprot ID

P60033

Purification

Purified

Antibody Clonality

Recombinant Monoclonal

Storage Note

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

Application Notes

The scFv version of this antibody is based on an anti-CD81 clone whose binding specificity was determined via FACS that was successfully used in an inhibition assay against HCV (Ji et al., 2015; PMID: 25417967). The exact binding site of this antibody was determined via crystallization (Nelson et al., 2018; PMID: 29778602). The scFv version of this antibody was used successfully in FC (Susa et al., 2020; PMID: 32338599).

Short Description

This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.